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CD3 Antikörper (violetFluor™ 450)

CD3 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 17A2 violetFluor™ 450

Produktnummer ABIN2567483

Datenblatt (PDF)

Target Alle CD3 Antikörper anzeigen

CD3
Reaktivität
211

105

33

20

17

10

8

8

7

7

7

3

3

2

2
Maus
Wirt
255

54

20

13

9

1
Ratte
Passende Sekundärantikörper
Klonalität
341

6

1
Monoklonal
Konjugat
102

43

35

26

25

13

10

8

8

8

6

5

5

5

5

4

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD3 Antikörper ist konjugiert mit violetFluor™ 450
Applikation
304

93

62

60

46

43

43

23

17

10

9

8

7

7

6

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

17A2

Isotyp

IgG2b kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.2 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD3

Andere Bezeichnung

CD3 (CD3 Produkte)

Hintergrund

The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains γ, δ, and ε subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 ε chain.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

Gen-ID

12501

UniProt

P22646

Pathways

T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway