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CD3 Antikörper

CD3 Reaktivität: Maus FACS, IP, IHC, Func Wirt: Ratte Monoclonal 17A2 unconjugated

Produktnummer ABIN2567480

Datenblatt (PDF)

Target Alle CD3 Antikörper anzeigen

CD3
Reaktivität
217

111

35

20

17

10

8

8

7

7

7

3

3

2

2
Maus
Wirt
263

60

20

13

9

2
Ratte
Passende Sekundärantikörper
Klonalität
355

6

1
Monoklonal
Konjugat
105

43

35

26

25

13

10

9

8

8

8

6

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD3 Antikörper ist unkonjugiert
Applikation
318

94

62

60

47

44

42

24

17

10

9

8

7

7

6

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Functional Studies (Func)

Spezifität

The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Klon

17A2

Isotyp

IgG2b kappa

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CD3 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-57 APC

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

2 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C. Do not freeze.
Target

CD3

Andere Bezeichnung

CD3 (CD3 Produkte)

Hintergrund

The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains γ, δ, and ε subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 ε chain.

Gen-ID

12501

UniProt

P22646

Pathways

T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway