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PD-1 Antikörper (FITC)

PDCD1 Reaktivität: Human FACS Wirt: Maus Monoclonal MIH4 FITC

Produktnummer ABIN2567416

Datenblatt (PDF)

Target Alle PD-1 (PDCD1) Antikörper anzeigen

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
Reaktivität
160

92

26

5

3

1
Human
Wirt
85

80

42

13

4

2

2

2

1
Maus
Passende Sekundärantikörper
Klonalität
165

60

5
Monoklonal
Konjugat
116

16

13

13

7

6

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser PD-1 Antikörper ist konjugiert mit FITC
Applikation
144

68

52

51

39

20

13

13

13

11

11

11

10

7

6

5

4

4

4

4

3

3

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

MIH4

Isotyp

IgG1 kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung

CD279 (PDCD1 Produkte)

Hintergrund

The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein. It is expressed on mainly on activated B, T, and myeloid cells. Within the cytoplasmic region, PD-1 contains an Immunoreceptor tyrosine-based inhibitory motif (ITIM) and seems to regulate peripheral tolerance. The lack or mutation of CD279 is linked to autoimmune disorders.

Gen-ID

5133

UniProt

Q15116

Pathways

Cancer Immune Checkpoints