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Integrin beta 2 Antikörper

ITGB2 Reaktivität: Maus FACS, Func Wirt: Ratte Monoclonal M18-2 unconjugated

Produktnummer ABIN2567290

Datenblatt (PDF)

Target Alle Integrin beta 2 (ITGB2) Antikörper anzeigen

Integrin beta 2 (ITGB2)
Reaktivität
197

60

43

9

7

3

3

3

2

2

2

2

2

2

2

1

1
Maus
Wirt
99

93

42

2

1

1
Ratte
Passende Sekundärantikörper
Klonalität
144

89

2
Monoklonal
Konjugat
107

23

21

16

9

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Dieser Integrin beta 2 Antikörper ist unkonjugiert
Applikation
138

84

56

47

39

33

31

26

26

25

22

12

12

4

3

3

3

2

2

1

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Spezifität

The M18/2 monoclonal antibody specifically binds to mouse CD18, a 95kDA integrin beta 2 glycoprotein.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Klon

M18-2

Isotyp

IgG2a kappa

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anti-Integrin beta 2 (ITGB2) antibody
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ITGB2 Reaktivität: Human FACS, WB, IP, IHC (fro), IHC (p) Wirt: Maus Monoclonal MEM-48 Biotin

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ITGB2 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-48 FITC

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ITGB2 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-48 PE

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ITGB2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reaktivität: Maus FACS, WB, IP, IHC (fro), Func, IHC (p) Wirt: Ratte Monoclonal M18-2 unconjugated

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ITGB2 Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 3C11G5 unconjugated

anti-Integrin beta 2 (ITGB2) (AA 17-382) antibody
ITGB2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reaktivität: Maus FACS, WB, IP, IHC (fro), IHC (p) Wirt: Ratte Monoclonal M18-2 unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C. Do not freeze.
Target

Integrin beta 2 (ITGB2)

Andere Bezeichnung

CD18 (ITGB2 Produkte)

Hintergrund

The M18/2 monoclonal antibody specifically binds to mouse CD18, a 95kDA integrin beta 2 glycoprotein. CD18 is expressed on all leukocytes with the highest density by NK and T cells. CD18 forms LFA-1 with CD11a, Mac-1 with CD11b and gp150/95 with CD11c. Through these interactions, CD18 has an important role in cellular adhesion. The M18/2 antibody is reported to stimulate Mac-1 and LFA-1 adhesion to their ligands and block tumor cell metastasis.

Gen-ID

16414

UniProt

P11835

Pathways

NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation