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CTLA4 Antikörper (APC)

CTLA4 Reaktivität: Human FACS Wirt: Maus Monoclonal BNI3 APC

Produktnummer ABIN2567243

Datenblatt (PDF)

Target Alle CTLA4 Antikörper anzeigen

CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Reaktivität
114

73

32

4

3
Human
Wirt
70

61

23

7

1

1

1

1
Maus
Passende Sekundärantikörper
Klonalität
99

62

3
Monoklonal
Konjugat
78

16

13

11

8

5

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CTLA4 Antikörper ist konjugiert mit APC
Applikation
94

64

59

32

22

17

13

12

10

7

7

6

4

4

4

3

2

2

2

2

2

1

1

1
Flow Cytometry (FACS)

Spezifität

The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4).

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

BNI3

Isotyp

IgG2a kappa

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anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibody
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anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibody
CTLA4 Reaktivität: Human FACS, IP, ICC, IHC (fro) Wirt: Maus Monoclonal BNI3 unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) antibody
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anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) antibody
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anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) antibody
CTLA4 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM50 unconjugated Recombinant Antibody

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 41-90) antibody
CTLA4 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 52-211) antibody
CTLA4 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 75-170) antibody
CTLA4 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (p), IF (p) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung

CD152 (CTLA4 Produkte)

Hintergrund

The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 (CD80) and B7-2 (CD86). The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes. CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it. This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28.

Gen-ID

1493

UniProt

P16410

Pathways

Cancer Immune Checkpoints