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ITGAL Antikörper

ITGAL Reaktivität: Maus FACS, Func Wirt: Ratte Monoclonal M17-4 unconjugated

Produktnummer ABIN2567123

Datenblatt (PDF)

Target Alle ITGAL Antikörper anzeigen

ITGAL (Integrin alpha-L (ITGAL))
Reaktivität
139

72

17

3

3

3

2

2

2

1

1

1
Maus
Wirt
111

53

50

1
Ratte
Passende Sekundärantikörper
Klonalität
172

42

1
Monoklonal
Konjugat
78

29

23

20

10

8

6

5

5

4

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser ITGAL Antikörper ist unkonjugiert
Applikation
152

46

41

36

30

29

24

21

9

8

6

6

4

2

2

2

2

1

1

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Spezifität

The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Klon

M17-4

Isotyp

IgG2a kappa

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anti-Integrin alpha-L (ITGAL) antibody
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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C. Do not freeze.
Target

ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung

CD11a (ITGAL Produkte)

Hintergrund

The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.

Gen-ID

16408

UniProt

P24063

Pathways

Activated T Cell Proliferation, Integrin Complex