ITGAL Antikörper
Kurzübersicht für ITGAL Antikörper (ABIN2567121)
Target
Alle ITGAL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein.
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Aufreinigung
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
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Isotyp
- IgG2a kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-buffered aqueous solution, ph7.2.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The product should be stored undiluted at 4°C. Do not freeze.
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- ITGAL (Integrin alpha-L (ITGAL))
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Andere Bezeichnung
- CD11a
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Hintergrund
- The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.
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Gen-ID
- 16408
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UniProt
- P24063
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Pathways
- Activated T Cell Proliferation, Integrin Complex
Target
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