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KIT Antikörper

KIT Reaktivität: Maus WB, FACS, IHC, ICC, Func Wirt: Ratte Monoclonal ACK2 unconjugated
Produktnummer ABIN2567112
  • Target Alle KIT Antikörper anzeigen
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Reaktivität
    • 585
    • 236
    • 63
    • 29
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    • 25
    • 16
    • 12
    • 5
    • 4
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 518
    • 101
    • 45
    • 2
    • 1
    Ratte
    Klonalität
    • 510
    • 157
    • 1
    Monoklonal
    Konjugat
    • 226
    • 64
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    • 60
    • 47
    • 46
    • 11
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    • 10
    • 10
    • 10
    • 10
    • 10
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIT Antikörper ist unkonjugiert
    Applikation
    • 355
    • 325
    • 284
    • 147
    • 91
    • 91
    • 65
    • 50
    • 44
    • 43
    • 34
    • 24
    • 10
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Functional Studies (Func)
    Spezifität
    The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene.
    Aufreinigung
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    Klon
    ACK2
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product KIT Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ph7.2.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The product should be stored undiluted at 4°C. Do not freeze.
  • Target
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Andere Bezeichnung
    CD117 (KIT Produkte)
    Hintergrund
    The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.
    Gen-ID
    16590
    UniProt
    P05532
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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