BAFF Antikörper

Produktnummer ABIN2470022

Der Maus Monoklonal Anti-BAFF-Antikörper wurde für ELISA, IHC und FACS validiert. Er ist geeignet, BAFF in Proben von Human zu detektieren.

Kurzübersicht für BAFF Antikörper (ABIN2470022)

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BAFF Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: T7-241

Produktdetails anti-BAFF Antikörper

Aufreinigung: Affinity Chromatography

Immunogen: TNFSF13B monoclonal antibody was raised against recombinant full length TNFSF13B (Human).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: TNFSF13B antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate-buffered solution, pH 7.2, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store TNFSF13B antibody at 4 °C. Do not freeze.

Details zu BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Andere Bezeichnung: TNFSF13B

Hintergrund: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-κ,B and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis.

Gen-ID: 10673

UniProt: Q9Y275

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response