BAFF Antikörper
Kurzübersicht für BAFF Antikörper (ABIN2470022)
Target
Alle BAFF (TNFSF13B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Affinity Chromatography
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Immunogen
- TNFSF13B monoclonal antibody was raised against recombinant full length TNFSF13B (Human).
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Isotyp
- IgG1
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Applikationshinweise
- TNFSF13B antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Phosphate-buffered solution, pH 7.2, 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store TNFSF13B antibody at 4 °C. Do not freeze.
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- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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Andere Bezeichnung
- TNFSF13B
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Hintergrund
- Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-κ,B and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis.
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Gen-ID
- 10673
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UniProt
- Q9Y275
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Pathways
- NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response
Target
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