BAFF Antikörper

Produktnummer ABIN1449224

Produktdetails anti-BAFF Antikörper

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BAFF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody reacts with human BAFF/BLyS.

Immunogen: Human BAFF/BLyS transfectant

Klon: 1D6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Protein A agarose, PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Andere Bezeichnung: CD257 / BAFF (TNFSF13B Produkte)

Synonyme: BAFF antikoerper, BLYS antikoerper, CD257 antikoerper, DTL antikoerper, TALL-1 antikoerper, TALL1 antikoerper, THANK antikoerper, TNFSF20 antikoerper, ZTNF4 antikoerper, BAFF-R antikoerper, BAFFR antikoerper, BROMIX antikoerper, CD268 antikoerper, CVID4 antikoerper, prolixin antikoerper, TNFSF13B antikoerper, RGD1561519 antikoerper, RGD1560810 antikoerper, BLyS antikoerper, D8Ertd387e antikoerper, zTNF4 antikoerper, 2010006P15Rik antikoerper, Baffr antikoerper, Bcmd antikoerper, Bcmd-1 antikoerper, Bcmd1 antikoerper, Lvis22 antikoerper, zgc:172115 antikoerper, TNF superfamily member 13b antikoerper, TNF receptor superfamily member 13C antikoerper, tumor necrosis factor (ligand) superfamily, member 13b antikoerper, tumor necrosis factor receptor superfamily, member 13c antikoerper, tumor necrosis factor superfamily member 13b antikoerper, TNFSF13B antikoerper, TNFRSF13C antikoerper, Tnfsf13b antikoerper, Tnfrsf13c antikoerper, tnfsf13b antikoerper

Hintergrund: BAFF (B cell-activating factor belonging to the TNF family) is a membrane protein expressed by dendritic cells, monocytes, macrophages, follicular dendritic cells, activated T cells, activated neutrophils, and malignant B cells. BAFF, also known as BLyS (B lymphocyte stimulator), is a potent B cell growth factor. Proteolytic cleavage can result in the release of a soluble trimeric BAFF which binds to the BAFF receptor, BCMA and TACI. The release of soluble BAFF is regulated by IFN-? and to a lesser extent IL-10. BAFF protects B cells from apoptosis and increases the expression of anti-apoptotic proteins Bcl-2 and Bcl-xL.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4

Gen-ID: 10673

NCBI Accession: NP_001139117

UniProt: Q9Y275

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response