Integrin beta 2 Antikörper (AA 534-546)

Produktnummer ABIN2469881

Der Maus Monoklonal Anti-Integrin beta 2-Antikörper wurde für FACS, WB, IHC und IP validiert. Er ist geeignet, Integrin beta 2 in Proben von Human zu detektieren.

Kurzübersicht für Integrin beta 2 Antikörper (AA 534-546) (ABIN2469881)

Target: Integrin beta 2 (ITGB2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: MEM-48

Produktdetails anti-Integrin beta 2 Antikörper

Bindungsspezifität: AA 534-546

Spezifität: Recongizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit, beta2 integrin).

Aufreinigung: Protein A Column

Immunogen: Integrin beta 2 monoclonal antibody was raised against Integrin beta 2 (Human).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Integrin beta 2 antibody can be used in ELISA starting at 1:100000, Western Blot starting at 1:1000 - 1:10000, and immunohistochemistry starting at 5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 15 mM sodium azide, approx., pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Integrin beta 2 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Details zu Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Andere Bezeichnung: Integrin beta 2

Hintergrund: CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes. The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Gen-ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation