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Insulin Receptor Antikörper (Internal Region)

INSR Reaktivität: Human, Affe, Gorilla, Gibbon IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2469537
  • Target Alle Insulin Receptor (INSR) Antikörper anzeigen
    Insulin Receptor (INSR)
    Bindungsspezifität
    • 16
    • 15
    • 13
    • 12
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 171
    • 97
    • 82
    • 16
    • 13
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Affe, Gorilla, Gibbon
    Wirt
    • 165
    • 27
    • 3
    • 1
    Kaninchen
    Klonalität
    • 157
    • 39
    Polyklonal
    Konjugat
    • 120
    • 16
    • 16
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Insulin Receptor Antikörper ist unkonjugiert
    Applikation
    • 142
    • 82
    • 51
    • 29
    • 18
    • 16
    • 16
    • 15
    • 13
    • 13
    • 8
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Spezifität
    BLAST analysis of the peptide immunogen showed no homology with other human proteins, except JARID2 (69 % ).
    Aufreinigung
    Immunoaffinity Chromatography
    Immunogen
    Insulin Receptor antibody was raised against a peptide located near the internal domain of Insulin Receptor (Human).
    Top Product
    Discover our top product INSR Primärantikörper
  • Applikationshinweise
    Insulin Receptor antibody can be used in ELISA starting at 1:10000, and immunohistochemistry starting at 1:200 - 1:400.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, 0.1 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    As with all antibodies avoid freeze/thaw cycles.
    Lagerung
    4 °C/-80 °C
    Informationen zur Lagerung
    Insulin Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
  • Target
    Insulin Receptor (INSR)
    Andere Bezeichnung
    Insulin Receptor (INSR Produkte)
    Synonyme
    CD220 antikoerper, HHF5 antikoerper, 4932439J01Rik antikoerper, D630014A15Rik antikoerper, IR antikoerper, IR-A antikoerper, IR-B antikoerper, 18402 antikoerper, CG18402 antikoerper, DIHR antikoerper, DILR antikoerper, DIR antikoerper, DIRH antikoerper, DIRbeta antikoerper, DInR antikoerper, DInr antikoerper, Dir-a antikoerper, Dir-b antikoerper, Dmel\\CG18402 antikoerper, INR antikoerper, INS antikoerper, Inr antikoerper, Inr-alpha antikoerper, Inr-beta antikoerper, InsR antikoerper, dINR antikoerper, dIR antikoerper, dIRH antikoerper, dInR antikoerper, dInr antikoerper, dInsR antikoerper, dinr antikoerper, dir antikoerper, er10 antikoerper, inr antikoerper, insulin/insulin-like growth factor receptor antikoerper, l(3)05545 antikoerper, l(3)93Dj antikoerper, l(3)er10 antikoerper, lnR antikoerper, ir-A antikoerper, CTK-1 antikoerper, ir antikoerper, INSR antikoerper, NV14476 antikoerper, cd220 antikoerper, hhf5 antikoerper, insulin receptor antikoerper, Insulin-like receptor antikoerper, insulin receptor L homeolog antikoerper, INSR antikoerper, Insr antikoerper, InR antikoerper, LOC100122567 antikoerper, LOC100451802 antikoerper, insr.L antikoerper
    Hintergrund
    INSR is an insulin receptor type protein kinase. Binding of insulin to INSR stimulates glucose uptake. Two insulin receptor mRNA transcripts resulting from alternative splicing of exon 11 in the receptor gene are expressed in a highly regulated tissue-specific fashion. Mutations in the INSR gene contribute to diseases, including of various forms of insulin resistance, insulin-resistant diabetes mellitus, noninsulin-dependent diabetes mellitus (NIDDM), Rabson-Mendenhall syndrome and Leprechaunism (Donohue Syndrome).
    Gen-ID
    3643
    UniProt
    P06213
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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