Insulin Receptor Antikörper (Internal Region)

Produktnummer ABIN2469537

Dieses Anti-Insulin Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Insulin Receptor in IHC. Geeignet für Human, Affe, Gibbon und Gorilla.

Kurzübersicht für Insulin Receptor Antikörper (Internal Region) (ABIN2469537)

Target: Insulin Receptor (INSR)

Reaktivität: Human, Affe, Gibbon, Gorilla

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Insulin Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-Insulin Receptor Antikörper

Bindungsspezifität: Internal Region

Spezifität: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except JARID2 (69 % ).

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Insulin Receptor antibody was raised against a peptide located near the internal domain of Insulin Receptor (Human).

Anwendungsinformationen

Applikationshinweise: Insulin Receptor antibody can be used in ELISA starting at 1:10000, and immunohistochemistry starting at 1:200 - 1:400.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Insulin Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Details zu Insulin Receptor

Target: Insulin Receptor (INSR)

Andere Bezeichnung: Insulin Receptor

Hintergrund: INSR is an insulin receptor type protein kinase. Binding of insulin to INSR stimulates glucose uptake. Two insulin receptor mRNA transcripts resulting from alternative splicing of exon 11 in the receptor gene are expressed in a highly regulated tissue-specific fashion. Mutations in the INSR gene contribute to diseases, including of various forms of insulin resistance, insulin-resistant diabetes mellitus, noninsulin-dependent diabetes mellitus (NIDDM), Rabson-Mendenhall syndrome and Leprechaunism (Donohue Syndrome).

Gen-ID: 3643

UniProt: P06213

Pathways: NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity