SPHK1 Antikörper (N-Term)

Produktnummer ABIN2469349

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPHK1 in IHC. Es zeigt Reaktivität gegenüber Proben von Human, Affe und Gibbon.

Kurzübersicht für SPHK1 Antikörper (N-Term) (ABIN2469349)

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Reaktivität: Human, Affe, Gibbon

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPHK1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-SPHK1 Antikörper

Bindungsspezifität: N-Term

Spezifität: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: SPHK1 antibody was raised against a peptide located in the N-Terminal domain of SPHK1 (Human).

Anwendungsinformationen

Applikationshinweise: SPHK1 antibody can be used in immunohistochemistry starting at 40 μg/mL, and flow cytometry.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: SPHK1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Details zu SPHK1

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Andere Bezeichnung: SPHK1

Hintergrund: Sphingosine kinase (SPHK) phosphorylates sphingosine to form a bioactive lipid mediate, sphingosine 1-phosphate (S1P or SPP). S1P is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival while extracellularly it is a ligand for EDG 1. Expression of SPHK1 and subsequent production of S1P promotes the G1-S transition, protects cells from apoptosis, stimulates migration and angiogenesis, and induces tumor formation in mice.

Gen-ID: 8877

UniProt: Q9NYA1

Pathways: VEGF Signaling