DDR1 Antikörper (C-Term)

Produktnummer ABIN2469321

Der Kaninchen Polyklonal anti-DDR1 Antikörper (ABIN2469321) detektiert spezifisch DDR1 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Affe, Schwein, Fledermaus, Pferd, Rind (Kuh), Hund, Schimpanse, Gibbon und Gorilla.

Kurzübersicht für DDR1 Antikörper (C-Term) (ABIN2469321)

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reaktivität: Human, Affe, Schwein, Fledermaus, Pferd, Rind (Kuh), Hund, Schimpanse, Gibbon, Gorilla

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-DDR1 Antikörper

Bindungsspezifität: C-Term

Spezifität: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DDR2 (69 % ).

Aufreinigung: Immunoaffinity Chromatography

Immunogen: DDR1 antibody was raised against a peptide located near the C-Terminal region of DDR1 (Human).

Anwendungsinformationen

Applikationshinweise: DDR1 antibody can be used in ELISA, Western Blot starting at 1 - 2 μg/mL, immunocytochemistry, immunohistochemistry starting at 10 μg/mL, immunoprecipitation starting at 1 - 2 μg/mL, and flow cytometry.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: DDR1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Details zu DDR1

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Andere Bezeichnung: DDR1

Hintergrund: DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors.

Gen-ID: 780

UniProt: Q08345

Pathways: RTK Signalweg, Smooth Muscle Cell Migration