Der Kaninchen Polyklonal Anti-EPH Receptor A4-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, EPH Receptor A4 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Affe, Kaninchen, Pferd, Schwein, Fledermaus, Hamster, Gibbon und Gorilla zu detektieren.
EPHA4 antibody can be used in immunohistochemistry starting at 7.3 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
As with all antibodies avoid freeze/thaw cycles.
Lagerung
4 °C/-80 °C
Informationen zur Lagerung
EPHA4 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Target
EPH Receptor A4 (EPHA4)
Andere Bezeichnung
EPHA4
Hintergrund
Nak1, a NR4 Nerve Growth Factor-Like receptor, has been shown to affect the hypothalamic-pituitary axis, neuronal differentiation, neuroendocrine regulation of adrenocortical function, and T-cell apoptosis. Nak1 also is known as nuclear receptor Tr3 and is similar to mouse Nur77 and rat NGFI-B. It is encoded by one of the immediate early genes (IEG) in response to nerve growth factor and other serum growth factors. Nak1 can bind to DNA as a monomer, homodimer, or heterodimer (with retinoid X receptors). Nak1 has been shown to inhibit vascular lesion formation and could serve as a novel target in the treatment of vascular diseases.