LDLR Antikörper (AA 29-205)

Produktnummer ABIN2467854

Der Huhn Polyklonal anti-LDLR Antikörper (ABIN2467854) detektiert spezifisch LDLR in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für LDLR Antikörper (AA 29-205) (ABIN2467854)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reaktivität: Human, Maus, Ratte

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser LDLR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LDLR Antikörper

Bindungsspezifität: AA 29-205

Aufreinigung: Antigen affinity-purified

Anwendungsinformationen

Applikationshinweise: LDL-R antibody can be used for the detection of LDL-R by Western blot, may also work for IHC and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Konservierungsmittel: Without preservative

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: LDLR antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Details zu LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Andere Bezeichnung: LDLR

Hintergrund: Low density lipoprotein receptor. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.

Molekulargewicht: 95.4 kDa (calculated)

Gen-ID: 3949

NCBI Accession: NP_000518

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism