C3 Antikörper

Produktnummer ABIN2467785

Dieses Anti-C3-Antikörper ist ein Huhn Polyklonal-Antikörper zur Detektion von C3 in ELISA. Geeignet für Human.

Kurzübersicht für C3 Antikörper (ABIN2467785)

Target: C3 (Complement Component 3 (C3))

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser C3 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-C3 Antikörper

Aufreinigung: Antigen affinity-purified

Immunogen: plasma protein

Anwendungsinformationen

Applikationshinweise: C3 antibody can be used for the detection of C3 by Western blot, ELISA, may also work for IHC and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Konservierungsmittel: Without preservative

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: C3 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Details zu C3

Target: C3 (Complement Component 3 (C3))

Andere Bezeichnung: Complement Component C3

Hintergrund: Human complement component C3. Complement C3 contains two chains linked by a disulfide bond. Its activation by a C3 convertase releases the C3a anaphylatoxin from the amino end of the alpha chain and generates C3b, which associates with the Bb fragment of complement factor B to form the alternative-complement-pathway C3/C5 convertase.C3a anaphylatoxin is a vasoactive peptide and a mediator of inflammation. C3b, with its highly reactive thiol group, binds to the surface of foreign particles and facilitates phagocytosis. It binds to complement C5 and renders it susceptible to proteolysis by the classical-complement-pathway C3/C5 convertase. The activity of C3b is regulated by proteolytic cleavage involving factors H and I. Its degradation products can also be biologically active.

Molekulargewicht: 187.2 kDa (calculated)

Gen-ID: 718

NCBI Accession: NP_000055

UniProt: P01024

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling