BLM Antikörper (pSer186)

Produktnummer ABIN2464128

Der Kaninchen Polyklonal anti-BLM Antikörper (ABIN2464128) detektiert spezifisch BLM in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Non-Human Primate.

Kurzübersicht für BLM Antikörper (pSer186) (ABIN2464128)

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Reaktivität: Human, Maus, Ratte, Non-Human Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BLM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-BLM Antikörper

Bindungsspezifität: pSer186

Aufreinigung: Affinity Purified

Immunogen: A synthetic peptide surrounding amino acid S186.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA, Western (immuno) blotting, Immunostaining (in testing)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Details zu BLM

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Hintergrund: The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids, including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.

Gen-ID: 641

UniProt: P54132

Pathways: DNA Reparatur