Bloom Syndrome (pSer527) Antikörper

Produktnummer ABIN2464127

Der Kaninchen Polyklonal Anti--Antikörper wurde für IHC, ELISA und WB validiert. Er ist geeignet, in Proben von Human, Maus, Non-Human Primate und Ratte zu detektieren.

Kurzübersicht für Bloom Syndrome (pSer527) Antikörper (ABIN2464127)

Target: Bloom Syndrome

Reaktivität: Human, Maus, Non-Human Primate, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Produktdetails

Bindungsspezifität: pSer527

Aufreinigung: Affinity Purified

Immunogen: A synthetic peptide surrounding amino acid S527

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA, Western (immuno) blotting, Immunostaining (in testing)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Antigendetails

Target: Bloom Syndrome

Hintergrund: The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids, including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.

Gen-ID: 641

UniProt: P54132