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Bloom Syndrome (pSer186) Antikörper

Reaktivität: Human, Maus, Non-Human Primate, Ratte IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2464128
  • Target
    Bloom Syndrome
    Bindungsspezifität
    • 8
    • 1
    • 1
    pSer186
    Reaktivität
    Human, Maus, Non-Human Primate, Ratte
    Wirt
    • 9
    Kaninchen
    Klonalität
    • 9
    Polyklonal
    Konjugat
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Aufreinigung
    Affinity Purified
    Immunogen
    A synthetic peptide surrounding amino acid S186.
    Isotyp
    IgG
  • Applikationshinweise
    ELISA, Western (immuno) blotting, Immunostaining (in testing)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Target
    Bloom Syndrome
    Hintergrund
    The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids, including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.
    Gen-ID
    641
    UniProt
    P54132
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