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RPS6KA1 Antikörper (truncated)

Der Maus Monoklonal Anti-RPS6KA1-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, RPS6KA1 in Proben von Human zu detektieren.
Produktnummer ABIN2464100

Kurzübersicht für RPS6KA1 Antikörper (truncated) (ABIN2464100)

Target

Alle RPS6KA1 Antikörper anzeigen
RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Reaktivität

  • 190
  • 103
  • 75
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 196
  • 17
Maus

Klonalität

  • 170
  • 44
Monoklonal

Konjugat

  • 105
  • 13
  • 12
  • 10
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
Dieser RPS6KA1 Antikörper ist unkonjugiert

Applikation

  • 172
  • 92
  • 54
  • 53
  • 49
  • 26
  • 24
  • 21
  • 12
  • 11
  • 9
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon

10B1D7A9-10B1D7E12
  • Bindungsspezifität

    • 33
    • 22
    • 19
    • 18
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    truncated

    Immunogen

    Ni-NTA purified truncated recombinant RSK1 expressed in E. Coli strain BL21 (DE3).

    Isotyp

    IgG2a
  • Applikationshinweise

    Western Blot:1:500 - 1:2,000
    IHC(P):1:500 - 1:2,000
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    RSK1 monoclonal antibody can be stored at -20 °C, stable for one year.
  • Target

    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

    Andere Bezeichnung

    RSK1

    Hintergrund

    Rsk1 is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK proteins possess two separate kinase domains, the C terminal kinase domain and the N terminal kinase domain, separated by a linker region containing a hydrophobic motif. RSK is activated by many stimuli including growth factors, phorbol esters, cAMP, heat shock, and irradiation.

    Gen-ID

    6195

    UniProt

    Q15418

    Pathways

    MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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