Fibulin 5 Antikörper (truncated)

Produktnummer ABIN2464054

Produktdetails anti-Fibulin 5 Antikörper

Target: Fibulin 5 (FBLN5)

Bindungsspezifität: truncated

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibulin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: Ni-NTA purified truncated recombinant Fibulin 5 expressed in E. Coli strain BL21 (DE3).

Klon: 3F8D5

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Western Blot:1:500 - 1:2000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: -20 °C

Informationen zur Lagerung: Fibulin 5 monoclonal antibody can be stored at -20 °C, stable for one year.

Details zu Fibulin 5

Target: Fibulin 5 (FBLN5)

Andere Bezeichnung: Fibulin5 (FBLN5 Produkte)

Hintergrund: Fibulin 5(FBLN5), with 448-amino acid protein (about 50 kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.

Gen-ID: 10516

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interaktom