NEU1 Antikörper

Produktnummer ABIN2462803

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NEU1 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für NEU1 Antikörper (ABIN2462803)

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEU1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-NEU1 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NEU1.

Anwendungsinformationen

Applikationshinweise: NEU1 antibody can be used for detection of NEU1 by ELISA at 1:312500. NEU1 antibody can be used for detection of NEU1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NEU1 antibody at -20 °C.

Details zu NEU1

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Andere Bezeichnung: NEU1

Hintergrund: NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.

Molekulargewicht: 40 kDa

Gen-ID: 4758

NCBI Accession: NP_000425

UniProt: Q99519

Pathways: SARS-CoV-2 Protein Interaktom