MSH2 Antikörper
Kurzübersicht für MSH2 Antikörper (ABIN2462390)
Target
Alle MSH2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Antibody is purified by protein A chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MSH2.
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Applikationshinweise
- MSH2 antibody can be used for detection of MSH2 by ELISA at 1:62500. MSH2 antibody can be used for detection of MSH2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Konzentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store MSH2 antibody at -20 °C.
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- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Andere Bezeichnung
- MSH2
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Hintergrund
- MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.
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Molekulargewicht
- 64 kDa, 105 kDa
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Gen-ID
- 4436
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UniProt
- P43246
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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