MSH2 Antikörper

Produktnummer ABIN2462390

Der Kaninchen-Polyklonal Anti-MSH2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet zum Nachweis von MSH2 in Proben aus Human, Maus, Hund und Zebrafisch (Danio rerio). }

Kurzübersicht für MSH2 Antikörper (ABIN2462390)

Target: MSH2 (Mismatch Repair Protein 2 (MSH2))

Reaktivität: Human, Maus, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MSH2 Antikörper

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MSH2.

Anwendungsinformationen

Applikationshinweise: MSH2 antibody can be used for detection of MSH2 by ELISA at 1:62500. MSH2 antibody can be used for detection of MSH2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MSH2 antibody at -20 °C.

Details zu MSH2

Target: MSH2 (Mismatch Repair Protein 2 (MSH2))

Andere Bezeichnung: MSH2

Hintergrund: MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.

Molekulargewicht: 64 kDa, 105 kDa

Gen-ID: 4436

UniProt: P43246

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response