PSMD11 Antikörper

Produktnummer ABIN2460632

Produktdetails anti-PSMD11 Antikörper

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMD11.

Anwendungsinformationen

Applikationshinweise: PSMD11 antibody can be used for detection of PSMD11 by ELISA at 1:312500. PSMD11 antibody can be used for detection of PSMD11 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMD11 antibody at -20 °C.

Details zu PSMD11

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Andere Bezeichnung: PSMD11 (PSMD11 Produkte)

Synonyme: psmd11 antikoerper, wu:fb55b06 antikoerper, zgc:56580 antikoerper, zgc:77763 antikoerper, Rpn6 antikoerper, S9 antikoerper, p44.5 antikoerper, 1700089D09Rik antikoerper, 1810019E17Rik antikoerper, 2610024G20Rik antikoerper, 2810055C24Rik antikoerper, C78232 antikoerper, P44.5 antikoerper, proteasome 26S subunit, non-ATPase 11 antikoerper, proteasome 26S subunit, non-ATPase 11b antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 antikoerper, PSMD11 antikoerper, psmd11b antikoerper, Psmd11 antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.

Molekulargewicht: 47 kDa

Gen-ID: 5717

NCBI Accession: NP_002806

UniProt: O00231

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway