PSMD11 Antikörper (C-Term)

Produktnummer ABIN389306

Produktdetails anti-PSMD11 Antikörper

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Bindungsspezifität: AA 288-317, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PSMD11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-317 amino acids from the C-terminal region of human PSMD11.

Klon: RB17375

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PSMD11

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Andere Bezeichnung: PSMD11 (PSMD11 Produkte)

Synonyme: psmd11 antikoerper, wu:fb55b06 antikoerper, zgc:56580 antikoerper, zgc:77763 antikoerper, Rpn6 antikoerper, S9 antikoerper, p44.5 antikoerper, 1700089D09Rik antikoerper, 1810019E17Rik antikoerper, 2610024G20Rik antikoerper, 2810055C24Rik antikoerper, C78232 antikoerper, P44.5 antikoerper, proteasome 26S subunit, non-ATPase 11 antikoerper, proteasome 26S subunit, non-ATPase 11b antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 antikoerper, PSMD11 antikoerper, psmd11b antikoerper, Psmd11 antikoerper

Hintergrund: The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.

Molekulargewicht: 47464

Gen-ID: 5717

NCBI Accession: NP_001257411, NP_002806

UniProt: O00231

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway