PAX6 Antikörper

Produktnummer ABIN2460553

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PAX6 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Zebrafisch (Danio rerio).

Kurzübersicht für PAX6 Antikörper (ABIN2460553)

Target: PAX6 (Paired Box 6 (PAX6))

Reaktivität: Human, Maus, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PAX6 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX6.

Anwendungsinformationen

Applikationshinweise: PAX6 antibody can be used for detection of PAX6 by ELISA at 1:62500. PAX6 antibody can be used for detection of PAX6 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAX6 antibody at -20 °C.

Details zu PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Andere Bezeichnung: PAX6

Hintergrund: PAX6 is one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA,This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.

Molekulargewicht: 48 kDa

Gen-ID: 5080

NCBI Accession: NP_001595

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis