K-RAS Antikörper

Produktnummer ABIN2459898

Produktdetails anti-K-RAS Antikörper

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Reaktivität: Human, Ratte, Maus, Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser K-RAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KRAS.

Anwendungsinformationen

Applikationshinweise: KRAS antibody can be used for detection of KRAS by ELISA at 1:62500. KRAS antibody can be used for detection of KRAS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KRAS antibody at -20 °C.

Details zu K-RAS

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Andere Bezeichnung: KRAS (KRAS Produkte)

Synonyme: wu:fa04e08 antikoerper, wu:fc14b12 antikoerper, wu:fc23g10 antikoerper, wu:fj89d12 antikoerper, zgc:85725 antikoerper, Kras2 antikoerper, c-Ki-ras antikoerper, p21 antikoerper, C-K-RAS antikoerper, CFC2 antikoerper, K-RAS2A antikoerper, K-RAS2B antikoerper, K-RAS4A antikoerper, K-RAS4B antikoerper, KI-RAS antikoerper, KRAS1 antikoerper, KRAS2 antikoerper, NS antikoerper, NS3 antikoerper, RASK2 antikoerper, AI929937 antikoerper, K-ras antikoerper, Ki-ras antikoerper, Kras-2 antikoerper, p21B antikoerper, ras antikoerper, k-ras antikoerper, kras antikoerper, kras-a antikoerper, kras-b antikoerper, rask2 antikoerper, K-RAS antikoerper, p21ras antikoerper, KRAS proto-oncogene, GTPase antikoerper, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog antikoerper, Kirsten rat sarcoma viral oncogene homolog antikoerper, semicolonial-7 antikoerper, Ras family protein antikoerper, GTPase KRas antikoerper, Kirsten rat sarcoma viral oncogene homolog S homeolog antikoerper, KRAS antikoerper, kras antikoerper, Kras antikoerper, smco-7 antikoerper, PGTG_03066 antikoerper, Tsp_02666 antikoerper, Tsp_01642 antikoerper, rask antikoerper, kras.S antikoerper

Substanzklasse: Viral Protein

Hintergrund: KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Molekulargewicht: 22 kDa

Gen-ID: 3845

NCBI Accession: NP_203524

UniProt: P01111