INSIG2 Antikörper

Produktnummer ABIN2458474

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch INSIG2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für INSIG2 Antikörper (ABIN2458474)

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INSIG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-INSIG2 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human INSIG2.

Anwendungsinformationen

Applikationshinweise: INSIG2 antibody can be used for detection of INSIG2 by ELISA at 1:62500. INSIG2 antibody can be used for detection of INSIG2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store INSIG2 antibody at -20 °C.

Details zu INSIG2

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Andere Bezeichnung: INSIG2

Hintergrund: INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 25 kDa

Gen-ID: 51141

NCBI Accession: NP_057217

UniProt: Q9Y5U4

Pathways: ER-Nucleus Signaling