INSIG2 Antikörper (N-Term)
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- Target Alle INSIG2 Antikörper anzeigen
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser INSIG2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- INSIG2 Antibody detects endogenous levels of total INSIG2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human INSIG2, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product INSIG2 Primärantikörper
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anti-Insulin Induced Gene 2 (INSIG2) (AA 50-150) antibody
INSIG2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) antibodyINSIG2 Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 Reaktivität: Human, Rind (Kuh), Ziege, Pferd, Kaninchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Pferd, Kaninchen, Hund, Schwein, Schaf WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
- Andere Bezeichnung
- INSIG2 (INSIG2 Produkte)
- Synonyme
- MGC82156 antikoerper, INSIG-2 antikoerper, 2900053I11Rik antikoerper, C730043J18Rik antikoerper, Insig-2 antikoerper, insulin induced gene 2 antikoerper, insulin induced gene 2 L homeolog antikoerper, insig2 antikoerper, insig2.L antikoerper, INSIG2 antikoerper, Insig2 antikoerper
- Hintergrund
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Description: Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
Gene: INSIG2
- Molekulargewicht
- 25 kDa
- Gen-ID
- 51141
- UniProt
- Q9Y5U4
- Pathways
- ER-Nucleus Signaling
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