INSIG2 Antikörper (AA 40-120)

Produktnummer ABIN7229148

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch INSIG2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für INSIG2 Antikörper (AA 40-120) (ABIN7229148)

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INSIG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-INSIG2 Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: Rabbit Anti-INSI2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of INSI2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human INSI2 protein at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu INSIG2

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Andere Bezeichnung: INSI2

Hintergrund: Insulin-induced gene 2 protein, INSIG-2INSIG2 (Insulin Induced Gene 2) is a Protein Coding gene. Among its related pathways are Metabolism and Sterol Regulatory Element-Binding Proteins (SREBP) signalling. The protein encoded by INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Molekulargewicht: 24kD

Gen-ID: 51141

UniProt: Q9Y5U4

Pathways: ER-Nucleus Signaling