PSMD12 Antikörper

Produktnummer ABIN2452114

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PSMD12 in WB und IP. Er zeigt eine Reaktivität gegenüber Saccharomyces cerevisiae und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für PSMD12 Antikörper (ABIN2452114)

Target: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Reaktivität: Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-PSMD12 Antikörper

Produktmerkmale: Product: Rabbit polyclonal antibody affinity purified with recombinant Rpn5p

Aufreinigung: Affinity purified

Immunogen: Recombinant yeast Rpn5p expressed in E. coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1) Western blotting: ~1000 fold dilution
2) Immunoprecipitation Not tested for other applications

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 mM NaCl, 10 mM Tris-HCl pH 7.4, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: To avoid repeated freezing and thawing, store the antibody solution in aliquots.

Lagerung: -20 °C

Referenzen für anti-PSMD12 Antikörper (ABIN2452114)

Isono, Nishihara, Saeki, Yashiroda, Kamata, Ge, Ueda, Kikuchi, Tanaka, Nakano, Toh-e: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." in: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).

Finley, Tanaka, Mann, Feldmann, Hochstrasser, Vierstra, Johnston, Hampton, Haber, Mccusker, Silver, Frontali, Thorsness, Varshavsky, Byers, Madura, Reed, Wolf, Jentsch, Sommer, Baumeister, Goldberg et al.: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." in: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).

Hershko, Ciechanover: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).

Details zu PSMD12

Target: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Andere Bezeichnung: Rpn5

Hintergrund: Background: The 26 S proteasome is a protein complex with a molecular mass of 2000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. Rpn5p is essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7. It consists of 445 amino acids with molecular weight of 51,768.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway