RAD51 Antikörper
Kurzübersicht für RAD51 Antikörper (ABIN2452093)
Target
Alle RAD51 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte (Rattus), Huhn
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Aufreinigung
- Purified
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Isotyp
- IgY
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Applikationshinweise
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1) Western blotting: 1,000~5,000 fold dilution
2) Immunoprecipitation
3) Detection of foci formation by indirect immunofluorescence method -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 100 mM NaCl, 20 mM phosphate buffer ( pH 7.4), 50 % glycerol
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
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Andere Bezeichnung
- Rad51
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Hintergrund
- Human Rad51 protein is a functional and structural homolog of E. coli RecA protein, which plays a major role in genetic recombination and recombination repair by mediating strand exchange reaction between homologous DNA strands. Rad51 functionally and physically interacts with its paralogs, Dmc1, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3, and also with Rad52 in recombination processes. It also interacts with oncogenes and tumor suppressors such as BRACA1, BRACA2, and P53 for the maintenance of genome stability.
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UniProt
- Q06609
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Pathways
- DNA Reparatur
Target
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