FFAR1 Antikörper (AA 210-222)

Produktnummer ABIN2450556

Dieses Anti-FFAR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FFAR1 in IHC. Geeignet für Human.

Kurzübersicht für FFAR1 Antikörper (AA 210-222) (ABIN2450556)

Target: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FFAR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-FFAR1 Antikörper

Bindungsspezifität: AA 210-222

Spezifität: GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes. The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7. GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.

Aufreinigung: Affinity purified

Immunogen: human GPR40 amino acids 210-222

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: TBS,  pH 7.4, containing 50 % glycerol, 0.5 mg/mL BSA, and 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, stable for 1 year. Avoid freeze-thaw cycles.

Details zu FFAR1

Target: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Andere Bezeichnung: FFAR1 / GPR40

Hintergrund: Name/Gene ID: FFAR1
Subfamily: Carboxylic Acid
Family: GPCR

Synonyms: FFAR1, FFAR, FFA1R, G protein-coupled receptor 40, GPCR40, GPR40, Free fatty acid receptor, Free fatty acid receptor 1, G-protein coupled receptor 40

Gen-ID: 2864

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis