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FFAR1 Antikörper (AA 143-178)

FFAR1 Reaktivität: Human ELISA, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7153159
  • Target Alle FFAR1 Antikörper anzeigen
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 143-178
    Reaktivität
    • 60
    • 32
    • 16
    • 5
    • 5
    • 3
    • 1
    • 1
    Human
    Wirt
    • 59
    • 2
    • 1
    Kaninchen
    Klonalität
    • 60
    • 2
    Polyklonal
    Konjugat
    • 22
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FFAR1 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 20
    • 13
    • 13
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Free fatty acid receptor 1 protein (143-178AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
    Andere Bezeichnung
    FFAR1 (FFAR1 Produkte)
    Synonyme
    FFAR1 antikoerper, GPR40 antikoerper, FFA1R antikoerper, GPCR40 antikoerper, Gpr40 antikoerper, free fatty acid receptor 1 antikoerper, FFAR1 antikoerper, Ffar1 antikoerper
    Hintergrund

    Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

    Aliases: FFA1R antibody, FFAR 1 antibody, Ffar1 antibody, FFAR1_HUMAN antibody, Free fatty acid receptor 1 antibody, G protein coupled receptor 40 antibody, G-protein coupled receptor 40 antibody, GPCR40 antibody, GPR 40 antibody, GPR40 antibody

    UniProt
    O14842
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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