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DUSP6 Antikörper

DUSP6 Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2428102
  • Target Alle DUSP6 Antikörper anzeigen
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    Reaktivität
    • 89
    • 58
    • 51
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 77
    • 11
    • 2
    • 1
    Kaninchen
    Klonalität
    • 73
    • 18
    Polyklonal
    Konjugat
    • 39
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DUSP6 Antikörper ist unkonjugiert
    Applikation
    • 63
    • 34
    • 13
    • 13
    • 11
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human DUSP6
    Isotyp
    IgG
    Top Product
    Discover our top product DUSP6 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Handhabung
    Avoid freeze / thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    Andere Bezeichnung
    MKP-3 (DUSP6 Produkte)
    Synonyme
    HH19 antikoerper, MKP3 antikoerper, PYST1 antikoerper, 1300019I03Rik antikoerper, MKP-3 antikoerper, Mkp3 antikoerper, wu:fd99d09 antikoerper, mkp3 antikoerper, pyst1 antikoerper, DUSP6 antikoerper, dusp6 antikoerper, dual specificity phosphatase 6 antikoerper, dual specificity phosphatase 6 L homeolog antikoerper, Dual specificity protein phosphatase 6 antikoerper, DUSP6 antikoerper, Dusp6 antikoerper, dusp6 antikoerper, dusp6.L antikoerper, dus6 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
    Pathways
    Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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