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GDF15 Antikörper (N-Term)

GDF15 Reaktivität: Human FACS, cELISA Wirt: Maus Monoclonal ME-6D10 unconjugated
Produktnummer ABIN238331
  • Target Alle GDF15 Antikörper anzeigen
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Bindungsspezifität
    • 16
    • 15
    • 11
    • 8
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-194, N-Term
    Reaktivität
    • 85
    • 29
    • 23
    • 1
    • 1
    Human
    Wirt
    • 84
    • 10
    • 2
    • 1
    Maus
    Klonalität
    • 85
    • 11
    • 1
    Monoklonal
    Konjugat
    • 48
    • 15
    • 9
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GDF15 Antikörper ist unkonjugiert
    Applikation
    • 83
    • 52
    • 36
    • 15
    • 13
    • 13
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    Aufreinigung
    Protein G
    Immunogen
    genetic immunisation with cDNA encoding aa30-194 (N-term) of MIC-1 proprotein
    Klon
    ME-6D10
    Isotyp
    IgG1
    Top Product
    Discover our top product GDF15 Primärantikörper
  • Applikationshinweise
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Kommentare

    Synonyms: GDF15

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C
    Informationen zur Lagerung
    short term: 2 °C - 8 °C, long term: -20 °C
  • Target
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Andere Bezeichnung
    MIC-1 (GDF15 Produkte)
    Synonyme
    GDF15 antikoerper, GDF-15 antikoerper, MIC-1 antikoerper, MIC1 antikoerper, NAG-1 antikoerper, PDF antikoerper, PLAB antikoerper, PTGFB antikoerper, SBF antikoerper, growth differentiation factor 15 antikoerper, GDF15 antikoerper, Gdf15 antikoerper
    Hintergrund
    Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-ß superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance. MIC-1 is synthesized as a 62-kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25-kDa disulphide-linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines. MIC-1 is involved in tumour pathogenesis and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. It could be a useful marker for aggressive prostate cancer while MIC-1 is upregulated in advanced and more aggressive prostatic tumours.
    UniProt
    Q99988
    Pathways
    SARS-CoV-2 Protein Interaktom
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