EGFR Antikörper (pTyr1068)
Kurzübersicht für EGFR Antikörper (pTyr1068) (ABIN232925)
Target
Alle EGFR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr1068
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Spezifität
- Recognizes endogenous levels of human EGF receptor at ~175kD only when phosphorylated at Tyr1068 at 175kD. The antibody may cross-react with other activated EGF receptor family members (e. g., ErbB2), and cross-reacts slightly with activated PDGF receptor.
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Aufreinigung
- Immunoaffinity purified
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Immunogen
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Synthetic phosphopeptide corresponding to residues surrounding Tyr1068 of human EGF receptor (KLH).
Type of Immunogen: Synthetic phospho-peptide -
Isotyp
- IgG
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Applikationshinweise
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Approved: ELISA, IHC, IHC-P, WB (1:1000)
Usage: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Western Blot: 1:1000. Immunohistochemistry (Paraffin): 1:50-350. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Andere Bezeichnung
- EGFR
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Hintergrund
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Name/Gene ID: EGFR
Subfamily: EGF Receptor
Family: Protein Kinase
Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1 -
Gen-ID
- 1956
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UniProt
- P00533
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
Target
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