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CD40 Ligand Antikörper (FITC)

CD40LG Reaktivität: Maus FACS, IP, Func Wirt: Hamster Monoclonal MR1 FITC

Produktnummer ABIN226480

Datenblatt (PDF)

Target Alle CD40 Ligand (CD40LG) Antikörper anzeigen

CD40 Ligand (CD40LG)
Reaktivität
157

86

34

9

8

6

5

3

2

2

2

2

2

2

1

1

1
Maus
Wirt
94

75

24

17

11

1
Hamster
Klonalität
130

87

4
Monoklonal
Konjugat
111

22

21

14

10

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD40 Ligand Antikörper ist konjugiert mit FITC
Applikation
123

101

56

50

39

29

21

18

16

14

13

13

7

5

5

4

4

4

3

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Spezifität

Recognizes CD154 (mouse CD40 ligand/gp39), Mr 39kD. Binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens, yet does not alter the immune response to TI antigens.

Aufreinigung

Purified

Immunogen

Activated mouse Th1 clone D1.6.

Type of Immunogen: Cells

Klon

MR1

Isotyp

IgG kappa

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anti-CD40 Ligand (CD40LG) antibody (FITC)
CD40LG Reaktivität: Maus FACS Wirt: Armenischer Hamster Monoclonal MR-1 FITC

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CD40LG Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 33-62) antibody
CD40LG Reaktivität: Human WB, FACS, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

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CD40LG Reaktivität: Schwein WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) antibody (PE)
CD40LG Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal 24-31 PE

anti-CD40 Ligand (CD40LG) (AA 47-261) antibody
CD40LG Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 8H10F5 unconjugated

Applikationshinweise

Approved: Flo, Func, IP

Usage: Flow cytometry. Immunoprecipitation. In vivo and in vitro blockage of CD154 function. Flow Cytometry: 2 μg/1 x10⁶. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare

Target Species of Antibody: Mouse

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS, sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
Target

CD40 Ligand (CD40LG)

Andere Bezeichnung

CD40LG / CD40L / CD154 (CD40LG Produkte)

Hintergrund

Name/Gene ID: CD40LG
Family: TNF

Synonyms: CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein

Gen-ID

959

UniProt

P29965

Pathways

NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints