CD40 Ligand Antikörper
Kurzübersicht für CD40 Ligand Antikörper (ABIN226478)
Target
Alle CD40 Ligand (CD40LG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes CD154 (mouse CD40 ligand/gp39), Mr 39kD. Binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens, yet does not alter the immune response to TI antigens.
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Aufreinigung
- Purified
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Immunogen
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Activated mouse Th1 clone D1.6.
Type of Immunogen: Cells -
Isotyp
- IgG kappa
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Applikationshinweise
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Approved: Flo, Func, IP
Usage: Flow cytometry. Immunoprecipitation. In vivo and in vitro blockage of CD154 function. -
Kommentare
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Target Species of Antibody: Mouse
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 100 mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
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Konservierungsmittel
- Without preservative
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- CD40 Ligand (CD40LG)
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Andere Bezeichnung
- CD40LG / CD40L / CD154
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Hintergrund
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Name/Gene ID: CD40LG
Family: TNF
Synonyms: CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein -
Gen-ID
- 959
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UniProt
- P29965
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Pathways
- NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
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