APC Antikörper (AA 1-433)
Kurzübersicht für APC Antikörper (AA 1-433) (ABIN224804)
Target
Alle APC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-433
-
Spezifität
- Recognizes the N-terminal region of the human APC protein. Epitope Mapping: Performed by differential in vitro expression of the N-terminal region of the APC gene by using the protein truncation test. Found to bind to APC in the region between aa135-422 (exon 2-3). Species cross-reactivity: Does not cross-react with mouse.
-
Aufreinigung
- Protein A purified
-
Immunogen
-
Synthetic peptide corresponding to aa1-433 N-terminal fragment of human APC (Adenomatous Polyposis Coli gene Chr 5q) (coupled to maltose binding protein). Cellular localization: cytoplasmic and nuclear.
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
-
Approved: IHC, IHC-Fr, WB
Usage: Suitable for use in Immunohistochemistry and Western Blot. Immunohistochemistry: Acetone fixed, frozen sections. Positive control: Colon cell line HCT116, SW480 and SW837 extracts. -
Kommentare
-
Target Species of Antibody: Human
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- PBS, pH 7.2, 40 % glycerol.
-
Handhabung
- Avoid repeat freeze-thaw cycles.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
-
-
- APC (Adenomatous Polyposis Coli (APC))
-
Andere Bezeichnung
- APC
-
Hintergrund
-
Name/Gene ID: APC
Synonyms: APC, Adenomatosis polyposis coli, Adenomatous polyposis coli, BTPS2, Deleted in polyposis 2.5, DP2, DP2.5, FPC, GS, Protein APC, PPP1R46, DP3 -
Gen-ID
- 324
-
UniProt
- P25054
-
Pathways
- WNT Signalweg, Stem Cell Maintenance, Cell-Cell Junction Organization
Target
-