PARP1 Antikörper (N-Term)
Kurzübersicht für PARP1 Antikörper (N-Term) (ABIN220760)
Target
Alle PARP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- Specifically recognizes the 85kD fragment of cleaved PARP and can be used as marker for detecting apoptotic cells. Species cross-reactivity: Human and bovine. Mouse and rat demonstrate 86 % homology.
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Aufreinigung
- Immunoaffinity purified
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Immunogen
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Synthetic peptide corresponding to N-terminus of cleavage site (214/215) of human PARP.
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG
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Applikationshinweise
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Approved: IHC, WB (1:1000)
Usage: Suitable for use in Western Blot, Immunohistochemistry. Western Blot: 1:1000. Positive control: HeLa and Jurkat cells treated with staurosporine. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Dulbecco's PBS (without Mg2+, Ca2+), pH 7.3, 50 % glycerol, 1 mg/mL BSA (IgG, protease free), 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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Andere Bezeichnung
- PARP1 / PARP
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Hintergrund
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Name/Gene ID: PARP1
Synonyms: PARP1, ADPRT, ADP-ribosyltransferase NAD(+), Adp-ribosyltransferase, ADPRT1, ARTD1, ADPRT 1, Poly(ADP-ribose) synthetase, Poly(ADP-ribosyl)transferase, PARP, Poly [ADP-ribose] polymerase 1, PADPRT-1, PARP-1, Poly (ADP-ribose) polymerase 1, Poly(ADP-ribose) polymerase, Poly[ADP-ribose] synthase 1, PPOL -
Gen-ID
- 142
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UniProt
- P09874
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Target
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