Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CD55 Antikörper

CD55 Reaktivität: Maus WB, FACS Wirt: Ratte Monoclonal 3D5 unconjugated
Produktnummer ABIN2192214
  • Target Alle CD55 Antikörper anzeigen
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Reaktivität
    • 117
    • 35
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    Maus
    Wirt
    • 74
    • 69
    • 6
    • 5
    • 4
    • 1
    • 1
    Ratte
    Klonalität
    • 89
    • 69
    • 2
    Monoklonal
    Konjugat
    • 74
    • 18
    • 16
    • 12
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD55 Antikörper ist unkonjugiert
    Applikation
    • 97
    • 82
    • 47
    • 39
    • 33
    • 26
    • 16
    • 15
    • 14
    • 13
    • 9
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Sterilität
    0.2 μm filtered
    Klon
    3D5
    Top Product
    Discover our top product CD55 Primärantikörper
  • Applikationshinweise
    It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Haltbarkeit
    12 months
  • Lin, Fukuoka, Spicer, Ohta, Okada, Harris, Emancipator, Medof: "Tissue distribution of products of the mouse decay-accelerating factor (DAF) genes. Exploitation of a Daf1 knock-out mouse and site-specific monoclonal antibodies." in: Immunology, Vol. 104, Issue 2, pp. 215-25, (2001) (PubMed).

    Harris, Spiller, Morgan: "Human and rodent decay-accelerating factors (CD55) are not species restricted in their complement-inhibiting activities." in: Immunology, Vol. 100, Issue 4, pp. 462-70, (2000) (PubMed).

    Spiller, Goodfellow, Evans, Almond, Morgan: "Echoviruses and coxsackie B viruses that use human decay-accelerating factor (DAF) as a receptor do not bind the rodent analogues of DAF." in: The Journal of infectious diseases, Vol. 181, Issue 1, pp. 340-3, (2000) (PubMed).

    Spiller, Harris, Morgan: "Efficient generation of monoclonal antibodies against surface-expressed proteins by hyperexpression in rodent cells." in: Journal of immunological methods, Vol. 224, Issue 1-2, pp. 51-60, (1999) (PubMed).

  • Target
    CD55 (Complement Decay-Accelerating Factor (CD55))
    Andere Bezeichnung
    Complement Decay Accelerating Factor (CD55 Produkte)
    Synonyme
    CR antikoerper, CROM antikoerper, DAF antikoerper, TC antikoerper, Daf antikoerper, Daf-GPI antikoerper, Daf1 antikoerper, GPI-DAF antikoerper, CD55 molecule (Cromer blood group) antikoerper, CD55 molecule, decay accelerating factor for complement antikoerper, CD55 antikoerper, Cd55 antikoerper
    Hintergrund
    The monoclonal antibody 3D5 recognizes complement decay accelerating factor (DAF), also designated as CD55. Cells express on their surface several proteins which protect against complement attack, namely C receptor I (CR1), decay accelerating factor (DAF), membrane cofactor protein (MCP) and CD59. CR1, DAF and MCP regulate the activation pathways of complement by either accelerating decay of the C3 and C5 convertase (CR1, DAF), or acting as cofactors for the serine protease factor I, which cleaves and irreversibly inactivates C3b (CR1, MCP). Mouse DAF (CD55) is a 60 kDa transmembrane protein that binds C3b and C4b to inhibit formation and half-life of the C3 convertases. DAF is broadly distributed among cells in contact with serum, including both haematopoietic and nonhaematopoietic cells. Although DAF does not have an essential role in controlling hemolysis of erythrocytes, it has an important role in regulation of the deposition of C3 on nucleated cells. Together with other complement regulators DAF protects self cells from autologous complement- mediated injury. DAF cooperates with CD46 in circumventing autologous C3 deposition, while CD59 inhibits the pathway at the critical end-point. DAF (decay accelerating factor), CD55 Aliases NRK cells expressing transmembrane-anchored mouse DAF Immunogen Rat IgG2a
    Pathways
    Komplementsystem, Regulation of Leukocyte Mediated Immunity
Sie sind hier:
Kundenservice