C3 Antikörper

Produktnummer ABIN2192120

Der Maus Monoklonal Anti-C3-Antikörper wurde für WB und IA validiert. Er ist geeignet, C3 in Proben von Ratte zu detektieren.

Kurzübersicht für C3 Antikörper (ABIN2192120)

Target: C3 (Complement Component 3 (C3))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser C3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoassay (IA)

Klon: 2B10B9B2

Produktdetails anti-C3 Antikörper

Endotoxin-Niveau: Low endotoxin level

Anwendungsinformationen

Applikationshinweise: For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 1 mL(> 100 μg/mL) culture medium with a low endotoxin level containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Haltbarkeit: 12 months

Details zu C3

Target: C3 (Complement Component 3 (C3))

Andere Bezeichnung: c3/c3b

Hintergrund: The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b. The antibody reacts both with intact C3 and C3b. The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha- chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes.

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling