DPP4 Antikörper

Produktnummer ABIN2192110

Dieses Maus Monoklonal-Antikörper erkennt spezifisch DPP4 in WB, IP, IHC (fro) und IA. Er zeigt eine Reaktivität gegenüber Ratte und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für DPP4 Antikörper (ABIN2192110)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DPP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)

Klon: 5E8

Produktdetails anti-DPP4 Antikörper

Sterilität: 0.2 μm filtered

Anwendungsinformationen

Applikationshinweise: For immunohistology and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Haltbarkeit: 12 months

Referenzen für anti-DPP4 Antikörper (ABIN2192110)

Ariyoshi, Mizuno, Morisue, Shimada, Fujita, Nasu, Okada, Shimomura, Yamamoto, Tsuji: "Identification of a target antigen recognized by a mouse monoclonal antibody to the bile canalicular surface of rat hepatocytes with a random phage display library." in: Acta medica Okayama, Vol. 56, Issue 4, pp. 187-91, (2002) (PubMed).

Hyodo, Mizuno, Yamada, Tsuji: "Distribution of asialoglycoprotein receptor in human hepatocellular carcinoma." in: Liver, Vol. 13, Issue 2, pp. 80-5, (1993) (PubMed).

Mizuno, Yamada, Sugiyama, Vierling, Brown: "Monoclonal antibodies identifying antigens on distinct domains of rat hepatocytes." in: Liver, Vol. 7, Issue 5, pp. 251-9, (1988) (PubMed).

Details zu DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Hintergrund: Dipeptidyl peptidase IV (DPP IV) is widely distributed in a number of mammalian tissues and is suggested to play an important role in various kinds of biological processes. DPP IV (CD26) is a serine-type protease that removes the amino-terminal dipeptide from peptide substrate provided that the penultimate amino acid residue is proline or alanine. DPP IV plays an important role in the reclamation of peptide nitrogen from larger peptides. The monoclonal antibody 5E8 reacts with DPP IV present on the apical surface of epithelial cells in the pancreas, small intestine, colon, and bile duct. Furthermore antibody 5E8 reacts with DPP IV on the laminar portions of the proximal renal tubule cells, and, weakly, on the glomeruli.

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity