FABP1 Antikörper

Produktnummer ABIN2191917

Produktdetails anti-FABP1 Antikörper

Target: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FABP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoassay (IA)

Kreuzreaktivität (Details): Cross reactivity: : Baboon L-FABP : Yes, Dog L-FABP : Yes, Rat L-FABP : Yes, Swine L-FABP : Yes, Human H-FABP Weak

Sterilität: 0.2 μm filtered

Klon: L2B10

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: For immunohistology and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Haltbarkeit: 12 months

Referenzen für anti-FABP1 Antikörper (ABIN2191917)

Bax, Siersema, Haringsma, Kuipers, Vos, Van Dekken, Van Vliet, Kusters: "High-grade dysplasia in Barrett's esophagus is associated with increased expression of calgranulin A and B." in: Scandinavian journal of gastroenterology, Vol. 42, Issue 8, pp. 902-10, (2007) (PubMed).

Details zu FABP1

Target: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Andere Bezeichnung: Liver Fatty Acid Binding Protein (FABP1 Produkte)

Hintergrund: The monoclonal antibody L2B10 recognizes human liver fatty acid binding protein (L-FABP) of both natural and recombinant origin. The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in the liver, kidney and intestinal epithelium. The monoclonal antibody L2B10 is useful to detect ischemic areas of human liver. Furthermore, the antibody can be used for the purification of human L-FABP. Aliases FABP1

Pathways: Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha