CD46 Antikörper
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- Target Alle CD46 Antikörper anzeigen
- CD46
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD46 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)
- Kreuzreaktivität (Details)
- Cross reactivity: Rat CD46 : Yes
- Sterilität
- 0.2 μm filtered
- Klon
- MM10
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD46 Primärantikörper
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- Applikationshinweise
- For immune histology, flow cytometry and western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilution. The typical starting working dilution is 1:50. IA: Rat CD46 or mouse CD46 variant as coating on a micro titer plate Positive control
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- Haltbarkeit
- 12 months
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-
The Role of Taste Receptor mTAS1R3 in Chemical Communication of Gametes." in: International journal of molecular sciences, Vol. 21, Issue 7, (2020) (PubMed).
: "
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The Role of Taste Receptor mTAS1R3 in Chemical Communication of Gametes." in: International journal of molecular sciences, Vol. 21, Issue 7, (2020) (PubMed).
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- Target
- CD46
- Andere Bezeichnung
- Membrane Cofactor Protein (CD46 Produkte)
- Synonyme
- AHUS2 antikoerper, MCP antikoerper, MIC10 antikoerper, TLX antikoerper, TRA2.10 antikoerper, Mcp antikoerper, CD46 antikoerper, CD46 molecule antikoerper, CD46 antigen, complement regulatory protein antikoerper, CD46 molecule, complement regulatory protein antikoerper, membrane cofactor protein-like antikoerper, CD46 antikoerper, Cd46 antikoerper, LOC100341359 antikoerper, LOC103789310 antikoerper
- Hintergrund
- The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46. MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic Neisseria. Aliases MCP, CD46, Trophoblast leukocyte common antigen, TLX, measles virus receptor Immunogen Mouse CD46-human Fc fusion protein
- Pathways
- Regulation of Actin Filament Polymerization
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