F11R Antikörper

Produktnummer ABIN2191795

Produktdetails anti-F11R Antikörper

Target: F11R (F11 Receptor (F11R))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser F11R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Kreuzreaktivität (Details): Cross reactivity: Human : No

Sterilität: 0.2 μm filtered

Klon: BV12

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: For flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.

Referenzen für anti-F11R Antikörper (ABIN2191795)

Martinez-Estrada, Manzi, Tonetti, Dejana, Bazzoni: "Opposite effects of tumor necrosis factor and soluble fibronectin on junctional adhesion molecule-A in endothelial cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 288, Issue 6, pp. L1081-8, (2005) (PubMed).

Details zu F11R

Target: F11R (F11 Receptor (F11R))

Andere Bezeichnung: Junctional Adhesion Molecule-A (F11R Produkte)

Synonyme: CD321 antikoerper, JAM antikoerper, JAM1 antikoerper, JAMA antikoerper, JCAM antikoerper, KAT antikoerper, PAM-1 antikoerper, 9130004G24 antikoerper, AA638916 antikoerper, ESTM33 antikoerper, JAM-1 antikoerper, JAM-A antikoerper, Jcam antikoerper, Jcam1 antikoerper, Ly106 antikoerper, Jam1 antikoerper, F11 receptor antikoerper, F11R antikoerper, F11r antikoerper

Hintergrund: The monoclonal antibody BV12 recognizes junctional adhesion molecule-A (JAM-A), also known as JAM-1 and the mouse platelet F11-Receptor (F11R), is a cell adhesion molecule (CAM). JAM-A is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-A belongs together with JAM-B (VE-JAM or JAM- 3) and JAM-C (JAM-2) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-A plays a role in platelet aggregation, secretion, adhesion and spreading. Aliases JAM-1, platelet F11-Receptor, F11R

Pathways: Cell-Cell Junction Organization